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Complex segregation analysis : ウィキペディア英語版 | Complex segregation analysis Complex segregation analysis (CSA) is a technique within genetic epidemiology to determine whether there is evidence that a major gene underlies the distribution of a given phenotypic trait. CSA also provides evidence to whether the implicated trait is inherited in a Mendelian dominant, recessive, or codominant manner. ==Purpose of CSA== CSA is often a preliminary step in genetic epidemiology. The purpose of CSA is to provide initial evidence that a single gene has a major effect on a particular phenotypic trait. Only phenotypic information, not genotypic information, is required for CSA. CSA can provide evidence, but not definitively prove a trait is under the control of a single gene. Evidence from CSA studies can be used to justify which phenotypes might be appropriate for more in-depth studies such as linkage analysis.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Complex segregation analysis」の詳細全文を読む
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